The Surviving Sepsis Campaign (SSC) bundle is the core of the Campaign's quality improvement efforts. Applying the sepsis bundle simplifies the complex processes of the care of patients with sepsis. The bundle is based on the 2016 guidelines recommendations integrating identified decision points and courses of action that when combined with clinical judgment, can make a difference in patient outcomes.
The Hour-1 bundle should be viewed as a quality improvement opportunity moving toward an ideal state. For critically ill patients with sepsis or septic shock, time is of the essence. Although the starting time for the Hour-1 bundle is recognition of sepsis, both sepsis and septic shock should be viewed as medical emergencies requiring rapid diagnosis and immediate intervention.
The Hour-1 bundle encourages clinicians to act as quickly as possible to obtain blood cultures, administer broad spectrum antibiotics, start appropriate fluid resuscitation, measure lactate, and begin vasopressors if clinically indicated. Ideally these interventions would all begin in the first hour from sepsis recognition but may not necessarily be completed in the first hour. Minimizing the time to treatment acknowledges the urgency that exists for patients with sepsis and septic shock.
*Note the description of the Hour-1 Bundle above is the most current having passed all approval points effective 1/10/19.
Hour-1 Bundle Pocket Card and Infographic (see more resources below)
Surviving Sepsis Campaign Hour-1 Bundle of Care Elements:
- Measure lactate level*
- Obtain blood cultures before administering antibiotics.
- Administer broad-spectrum antibiotics.
- Begin rapid administration of 30mL/kg crystalloid for hypotension or lactate level ≥ 4 mmol/L.
- Apply vasopressors if hypotensive during or after fluid resuscitation to maintain MAP ≥ 65 mm Hg.
* Remeasure lactate if initial lactate is elevated (> 2 mmol/L).
Hour-1 Bundle Teaching Slides
Hour-1 Bundle Pocket Card and Infographic
The Surviving Sepsis Campaign Bundle: 2018 Update Journal Publication
Critical Care Medicine
Intensive Care Medicine
A bundle is a selected set of elements of care that, when implemented as a group, have an effect on outcomes beyond implementing the individual elements alone.
Find more bundle implementation resources.